Advantages
- It has a directed antiviral, immunomodulatory and anti-inflammatory effect.
- Quickly improves well-being and reduces the duration of clinical symptoms of viral diseases.
- Prevents the development of complications after diseases.
Composition and pharmacological properties.
"ANANDIN® 10% solution for injection" as an active substance contains glucaminopropylcarbacridone – 100 mg/ml.
Glucaminopropylcarbacridone (ANANDINE®) is a low molecular weight cytokine inducer, stimulates the production of anti-inflammatory cytokines and endogenous interferon, which at the intracellular level suppresses the reproduction of viruses, preventing the development of infectious processes. It has an anti-inflammatory and immunomodulatory effect, increasing the functional activity of T-lymphocytes and macrophages, activates phagocytosis, which is primarily necessary for the treatment of viral and bacterial infections and complications after diseases due to increased immune protection.
With intramuscular administration of the drug glucaminopropylcarbacridone actively penetrates from the injection site into the systemic bloodstream, spreading throughout the body.
The maximum concentration of glucaminopropylcarbacridone in the blood of cattle and pigs is noted after 30 minutes, in the blood of dogs – after 1 hour. The compound is completely excreted unchanged in the urine, its accumulation does not occur in the animal's body, and even after repeated injections a day later, glucaminopropylcarbacridone is not detected in the blood and urine.
"ANANDIN® 10% solution for injection", according to the degree of exposure to the body, refers to moderately dangerous substances (hazard class 3 according to GOST 12.1.007). In the recommended doses, the drug does not have a locally irritating and allergenic effect.
Indications for use.
Cattle and pigs in the complex therapy of viral and bacterial infections, as well as complications after diseases; correction of immunodeficiency conditions under stress (transportation, weaning, regrouping); to increase the overall resistance of the body and the effectiveness of immunization.
Dogs in the complex therapy of viral infections, including canine plague.
Contraindications
Contraindication to the use of the drug "ANANDIN® 10% solution for injection" is an increased individual sensitivity of the animal to its components.
For females during pregnancy and feeding of the offspring, if necessary, "ANANDIN® 10% solution for injection" is used under the supervision of a veterinarian.
Dosage and administration procedure.
To cattle and pigs intramuscularly twice with an interval of 48 hours at a dose of 0.02 ml / kg of animal weight (corresponds to 2.0 mg of active substance per 1 kg of animal weight), regardless of age.
Dogs intramuscularly, once a day at a dose of 0.15-0.2 ml / kg of animal weight (corresponds to 15-20 mg of active substance per 1 kg of animal weight), regardless of age. Treatment is recommended to begin at the early stages of the disease, in this case the drug is administered for 3 consecutive days, with a late start of treatment, the course of application is extended to 4-6 days.
To increase the effectiveness of immunization, "ANANDIN® 10% solution for injection" is administered to animals once 24 hours before the use of the vaccine in doses specified for the corresponding type of animal.
Side effects.
Side effects and complications when using Anandine 10% solution for injection in accordance with this instruction, as a rule, are not observed. With increased individual sensitivity of the animal to the active components of the drug and the appearance of signs of allergy, the use of the drug is discontinued.
Storage.
Store "ANANDIN® 10% solution for injection" in a closed manufacturer's packaging, in a place protected from direct sunlight, at a temperature from 2 ° C to 25 ° C.
The shelf life of the drug, subject to storage conditions in the manufacturer's closed packaging, is 2 years from the date of production, after opening the bottle -28 days.
