Koliflox solution for oral use
- High-effective combined broad-spectrum antibacterial drug against diseases in pigs and poultry.
- Oral dosage form is convenient for group administration.
- Long-term absence of microorganism tolerance.
Chemical composition and pharmacological properties100 ml contain enrofloxacin - 10 g and colistin sulfate - 100,000,000 IU as active ingredients.
Combination of enrofloxacin and colistin sulfate has synergistic effect providing broad-spectrum antimicrobial activity against gram-positive and gram-negative microorganisms.
Enrofloxacin (a fluroquinolone compound) is active against Escherichia coli, Haemophilus spp., Pasteurella spp., Salmonella spp., Staphylococcus spp., Streptococcus spp., Clostridium perfringens, Bordetella spp., Campylobacter spp., Corynebacterium pyogenes, Pseudomonas aeruginosa and Mycoplasma spp.
Colistin sulfate (a polypeptide antibiotic) is active against Escherichia coli, Pseudomonas aeruginosa, Klebsiella spp., Salmonella spp., Proteus spp.
After oral administration enrofloxacin well and rapidly absorbs in gastrointestinal tract penetrating within most of organs and tissues; colistin sulfate slightly absorbs in gastrointestinal tract and does not accumulate in organs and tissues. Mainly, it is excreted unchanged in feces.
IndicationsUse to treat and prevent poultry with colibacillosis, salmonellosis, chronic respiratory diseases, streptococcosis, necrotic enteritis, Glasser's disease, mycoplasmosis, combined infections and secondary ones associated with viral diseases; piglets with colibacillosis and bacterial enteritis, agents of which are susceptible to enrofloxacin and colistin.
ContraindicationsIt is not recommended to use in laying hens and henny replacements 2 weeks before start of egg-laying (due to enrofloxacin accumulation in eggs). Do not use in piglets < 20 kg and animals with renal and hepatic diseases, as well as in combination with levomycetin, macrolides, tetracyclines, theophyllin, polyether ionophores, nonsteroidal anti-inflammatory drugs and magnesium and calcium supplements.
Dosage and administrationBroiler chickens, breeding poultry, replacements of hens and turkeys: administer by rearing in daily dose of 0.5 ml per 1 l of drinking water within 3-5 days; salmonellosis, combined infections and chronic diseases - 1 ml per 1 l of water for at least 5 days. Only water with the drug is allowed to be consumed during treatment. Piglets: administer by rearing with potable water (1:1), daily dose is 0.3 ml/kg of body weight, once a day within 2-3 days.
Adverse eventsIn case of increased individual sensitivity to active ingredients, feed refusal, vomiting and motor dysfunction may be observed. In case of adverse events, stop drug administration.
Waiting periodPoultry and piglets are allowed to be slaughtered for meat in 11 and 14 days, respectively, after the last drug administration. Meat of compulsorily slaughtered animals received before stated period termination can be used to feed animals or reworked to tankage.
StorageStore in original package at 5-25°С. Protect from direct sunlight and moisture.
Pharmaceutical form1 l plastic bottle, 2.5 and 5 l cans.
The information provided in this catalog is for reference only. There may be some changes in the characteristics, packaging and packaging of products.
AVZ reserves the right to make such changes without notice. You can get full information about the updated products from your personal manager or your nearest AVZ dealer.
All drugs for veterinary use from this catalog may be contraindicated and when using it is necessary to familiarize yourself with the Instructions for Use.