Delcid 7,5

Product benefits:

• Unique product.

• 100% effective against mature and larval forms.

• Ease of use - POUR-ON.

• No withdrawal period.

• Reduces the risk of vector-borne infectious diseases.

• Long-term insecticidal and repellent effect.

Chemical composition and pharmacological properties

1 ml of DELCID® 7.5 contains deltamethrin - 7.5 mg, diflubenzuron - 3 mg and piperonyl butoxide - 1.5 mg as active ingredients, as well as excipients: butylhydroxytoluene, butylated hydroxyanisole, diethylene glycol monoethyl ether.

Appearance: colorless to yellow liquid (opalescence is possible).

DELCID® 7.5 belongs to the group of combined intraacaricidal agents.

Deltamethrin ((1R)-cis-3-(2,2-dibromvinyl)-2,2-dimethyl cyclopropane carboxylic acid (S)-3-phenoxy-α-cyanbenzyl ether) which is a part of the product is a synthetic pyrethroid, has a strong insecticidal and repellent effect; it is effective against itch mites (Psoroptes, Chorioptes, Sarcoptes), Ixodes (Boophilus, Dermacentor, Haemaphisalis, Hyalomma, Ixodes, Rhipicephalus); blood-sucking insects, including horseflies (Pangonius, Nanorhynchus, Hepfatoma, Tabanus, Hybomitra, Atylotus, Phillipomya, Dasyrhamphis, Therioplectus, Chrysops, Haematopota, Silvius), gadflies (Hypoderma, Oedemagen, Grivellia, Oestrus Rhinoestrus, Cephenomia, Cephalopina, Gastrophilus), Mosquitoes (Aedes, Culex, Culiseta, Anopheles, Mansonia, Uranotaenia, Orthopodomyia), black flies (Simuladae), woodlice (Culicoides, Leptoconops, Lasiohelea), lice (Haematopinidae, Linognatidae, Holopeuridae), louse flies (Melophagus ovinus) and zoophilic flies (Haematobia irritons, Haematobia stìmulans, Musca domestica, Fannia canicula ris, Muscina stabulans, Musca autumnalis, Musca larvipara, Musca Amica, Wohlfahrtia magnifica, Stomoxys calcitrans, Lyperosia titilans, Lyperosia irritons).

The mechanism of action of deltamethrin is based on the block of the neuromuscular transmission of nerve stimuli at the level of peripheral nodes, which leads to uncontrolled activity of the central nervous system and the death of ectoparasites.

Diflubenzuron (3-(2,6-difluorobenzoyl)-1-(4-chlorophenyl)-urea) which refers to a group of chitin inhibitors disrupts hormonal processes of synthesis of chitin in the body of arthropod larvae, which disrupts the molting process, causing the formation of defected non-viable forms, the termination of egg laying, the development of larvae from eggs and replenishment of the population.

Piperonyl butoxide (5-[2-(2-butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxol) which is a synergist of pyrethroids, blocks the activity of monooxygenases and carboxyesterases of ectoparasites that play a role in detoxification of insecticides, improving penetration of pyrethroid through the cuticle, enhances its effect on the nervous system of the insect, accelerates the onset of paralysis.

After the topical application, the active substances in the composition of the drug are homogeneously distributed over the surface of skin virtually without absorption into bloodstream. They accumulate in the epidermis, hair follicles and sebaceous glands of an animal, and provide long-term contact insecticidal and repellent effect.

DELCID® 7.5 is effective against larval and imaginal phases of ectoparasite development, including those resistant to other insecticides; it blocks and/or impairs egg laying, hatchability of larvae, the formation of defected non-viable forms and replenishment of the ectoparasite population.

DELCID® 7.5 reduces the risk of vector-borne diseases carried by ticks and insects, including babesiasis, anaplasmosis, teileriosis, anthrax, tularemia, foot-and-mouth disease, tuberculosis, brucellosis, setariosis, moraxellosis, bluetongue, infectious nodular dermatitis of cattle, wolfarthiosis and onchocerciasis. After topical application DELCID® 7.5 causes the death of ectoparasites before the transmission of the pathogen to the animal.

According to the extent of exposure after oral and topical application, DELCID® 7.5 refers to the moderately hazardous substances. In recommended doses it does not have a local irritating effect, as well as allergenic and immunotoxic properties. After contact with eyes, it causes mild irritation of the mucous membranes. The drug is toxic to bees, as well as to fish and other aquatic organisms.

Indications

DELCID® 7.5 is used for treatment of cattle, sheep and goats to destroy ectoparasites and protect animals from their attacks.

Contraindications

DELCID® 7.5 is contraindicated in cases of individual hypersensitivity of the animal to the components of the drug. Do not administer the drug to dairy sheep whose milk is used for food purposes.

Dosage and administration

The treatment of animals is carried out according to indications outdoor or in a well-ventilated room, by applying the drug to the dry and undamaged skin on the back from the head to the base of the tail along the spine using a dispenser. The drug is applied once at doses indicated in the table.

Protective effect after a single application of DELCID® 7.5, depending on the number of ectoparasites and weather conditions, lasts 4–5 weeks against ixodic mites and 8–10 weeks against insects. Repeated treatment is carried out according to indications, but not more than once every 28 days.

Before mass treatments, each batch of the drug is tested on 10–15 animals with different nutritional status. If the animals do not show signs of hypersensitivity to the components of the drug within two days after treatment, treatment of the entire livestock is carried out. Lactating cows are treated immediately after milking, sheep of the same herd are treated simultaneously after shearing.

Side effects

DELCID® 7.5 when used in accordance with this instruction usually does not cause side effects or complications. In individual hypersensitivity and allergic reactions, the drug is washed off with water and, if necessary, antihistamines and symptomatic therapy are prescribed.

Special warnings

Do not apply DELCID® 7.5 on wet, damaged and contaminated skin of an animal.

DELCID® 7.5 should not be co-administered with other insecticidal drugs due to a possible mutual potentiation of the toxicity.

After treatment of animals with DELCID® 7.5 in accordance with the instructions, slaughter products and cattle milk can be used without restrictions, sheep slaughter products - not earlier than 3 days after the last application of the drug. The meat of sheep forcibly slaughtered before the expiration of the specified period can be used to feed fur-bearing animals.

Storage

The drug is stored in a closed original packaging, in a place protected from direct sunlight, at 2 °C to 25 °C.

The shelf life of the drug stored in accordance with instructions in a closed manufacturer's packaging is 3 years from the date of manufacture, in an opened package - 8 months. Do not use after the expiry date.