Ciprovet-pulmo powder for oral use
- Due to synergism of active substances, drug efficiency is significantly higher than in particular components.
- Broad-spectrum antibacterial and mycoplasmal effect.
- Rapidly absorbs in gastrointestinal tract.
- Peak blood concentration is observed in 1-1.5 hours. Therapeutic concentration is maintained within 24 hours.
- Combination of active ingredients prevents development of microorganism resistance to fluroquinolones.
Chemical composition and pharmacological properties1 g of powder contains ciprofloxacin - 100 mg and tiamulin hydrogen fumarate - 450 mg as active ingredients.
Ciprovet-pulmo is a combined antibacterial drug.
Ciprofloxacin is a fluroquinolone antibiotic with broad-spectrum antibacterial and antimycoplasmal properties. It is active against gram-positive and gram-negative bacteria (including Echerichia coli, Salmonella spp., Shigella spp., Klebsiella spp., Enterobacter spp., Proteus spp., Yersinia spp., Haemophilus spp., Pseudomonas aeruginosa, Pasteurella multocida, Plesiomonas shigelloides, Campylobacter jejuni, Brucella spp., Chlamydia trachomatis, Listeria monocytogenes, Mycobacterium spp., Corynebacterium diphtheriase, Staphylococcus aureus, Streptococcus spp. and Mycoplasma spp.).
Tiamulin hydrogen fumarate (a pleuromutilin antibiotic) provides bacteriostatic effect on mycoplasma (including М. hyopneumoniae, M. hyosynoviae, M. hyorhinis, M. gallisepticum, M. synoviae, M. meleagridis), Spirochaeta (B. huodysenteriae, B. pilosicoli), gram-positive aerobes (including Staphylococcus spp., Streptococcus spp., Corynebacterium pyogenes) and anaerobes (Clostridiym perfringens), gram-negative anaerobes (including Lawsonia intracellularis, Bacteroides spp., Fusobacterium spp.) and aerobes (Actinobacillus pleuropneumoniae, Pasteurella multocida).
Ciprofloxacin obtains peak serum concentration in 1.5-2 hours. Therapeutic concentration remains within 24 hours.
Tiamulin hydrogen fumarate rapidly absorbs in gastrointestinal tract and penetrates in most of organs and tissues obtaining peak concentration in pigs and poultry in 3 hours. It remains at therapeutic level within 18-24 hours.
IndicationsUse Ciprovet-pulmo to treat pigs or treat and prevent hens and turkeys with bacterial/mycoplasmal respiratory and gastrointestinal infections (including enzootic pneumonia, pleuropneumonia, salmonellosis, mycoplasmosis, colibacillosis) and others, agents of which are susceptible to ciprofloxacin and tiamulim.
ContraindicationsIncreased individual sensitivity to the drug components. Do not use in laying hens with esculent eggs, pregnant sows and animals with frank renal/hepatic impairment. It is not allowed to use in combination with monensin, salinomycin, narasin and other ionophoric coccidiostatic preparations (within 7 days before and after administration), as well as with aminoglycoside antibiotics, levomycetin, macrolides, tetracyclines, theophyllin and nonsteroidal anti-inflammatory drugs.
AdministrationOral individual or group administration with drinking water or feed. Treatment: pigs - 0.045 g per 1 kg of body weight. Daily dose consumption is provided by rearing of drug solution (400 g of powder per 1 ton of water). The course of use is 5-10 days.
Treatment and prevention: broiler chickens, replacements under 16 weeks old and parent livestock of hens and turkeys - 0.11 g per 1 kg of body weight. Daily dose consumption is provided by rearing of drug solution (550 g of powder per 1 ton of water). The course of use is 3-5 days.