AMOXIYANTAR GRANULES

Benefits

• A drug with antimicrobial and antioxidant effects for rapid recovery and rehabilitation of an animal.

• Stimulates degradation of bacterial biofilms in the body of animals.

• Improves sensitivity of organisms by increasing the permeability of bacterial cell membranes.

• Heat-resistant granulate

Composition and pharmacological properties.

1 g of "Amoxiyantar granules" contain 115 mg of amoxicillin (in the form of trihydrate) as active ingredient; succinic acid, RUSNUT bulking agent, paraffin oil as excipients.

Appearance: yellow to brown granules with dark inclusions.

"Amoxiyantar granules" belongs to the penicillins pharmacotherapeutic group.

Amoxicillin trihydrate, which is an ingredient of the product, has a broad-spectrum antibacterial effect against most Gram-positive and Gram-negative organisms, including: Staphylococcus spp., Streptococcus spp., Corynebacterium spp., Pasteurella spp., Haemophilus spp., Actinobacillus spp., Escherichia coli, Salmonella spp., Moraxella spp., Fusobacterium spp., Clostridium spp., Bordetella spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes.

Amoxicillin is a semi–synthetic antibiotic from the group of penicillins. The mechanism of action of amoxicillin is based on the inhibition of the functions of bacterial enzymes transpeptidases localized on the cytoplasmic membrane of a microbial cell. Through binding to transpeptidases, amoxicillin inhibits the synthesis of murein, the main material for the bacterial cell wall. As a result, the product affects osmotic balance of the microbial cell, makes the outer shell less stable and thereby causes bacterial lysis.

Amoxicillin is a semi–synthetic antibiotic from the group of penicillins. The mechanism of action of amoxicillin is based on suppression of the functions of bacterial enzymes transpeptidases localized on the cytoplasmic membrane of a microbial cell.

Through binding to transpeptidases, amoxicillin inhibits the synthesis of murein, the main material for the bacterial cell wall. As a result, the product affects osmotic balance of the microbial cell, makes the outer shell less stable and thereby causes bacterial lysis.

After oral administration amoxicillin is readily and rapidly absorbed in the gastrointestinal tract and, reaching the bloodstream, penetrates into all organs and tissues of the body. Time to maximum serum concentration is 1 hour post-dose. Amoxicillin is excreted with urine and feces mainly in unchanged form.

Indications.

"Amoxiyantar granules" are prescribed to pigs for treatment of respiratory, gastrointestinal and other primary and secondary bacterial diseases caused by pathogens sensitive to amoxicillin.

Contraindications.

Amoxiyantar granules are contraindicated in animals with individual hypersensitivity to beta-lactam antibiotics, as well as in severe liver and kidney injury.

How to use.

"Amoxiyantar granules" is used individually or in groups in a mixture with feed at a daily dose of 10-20 mg of amoxicillin trihydrate per 1 kg of animal bodyweight (equivalent to 100-200 mg/kg bodyweight or 2.5-5.0 kg of the drug per 1 ton of feed) for 5-10 days.

Throughout the treatment period, pigs should receive food containing the drug.

Amoxiyantar granules are thermally stable, which makes it possible to introduce the drug into the composition of feeds, produced with the use of short-term heat treatment technology.

Side effects.

When Amoxiyantar granules are used in accordance with this instructions, the risk of side effects and complications is low. In case of allergic reactions, discontinue treatment with Amoxiyantar granules and start antihistamines and symptomatic therapy.

Withdrawal period.

Do not co-administer of "Amoxiyantar granules" with bacteriostatic antibiotics (tetracyclines, macrolides) due to a possible antagonistic effect.

Slaughter of pigs for meat is allowed not less than 5 days after the last dose of the product. The meat of pigs forcibly slaughtered before the expiration of the specified period can be used to feed fur-bearing animals.

Storage.

The shelf life of the drug stored in accordance with instructions in a closed manufacturer's packaging, is 3 years from the date of manufacture, in an opened package - 3 months. Do not use after the expiry date.

The drug is stored in a closed original packaging, in a place protected from moisture and direct sunlight, at 2°C to 25°C.